Inflammaging: Why Your Skin Feels Like It’s Aging Faster Than You Are
- Eza Borchardt
- May 14
- 4 min read

You’re Not Aging—You’re Running on Low Power
Tired skin. Uneven texture. A glow that doesn’t bounce back the way it used to.
You haven’t done anything “wrong.” But your skin might be caught in a quiet storm of slow-burning inflammation and low cellular energy—a state researchers call inflammaging.
It’s not just about wrinkles or elasticity. It’s about your skin’s ability to regenerate itself.
Let’s decode how stress, metabolism, and cellular repair shape the way you age—and how to return to your glow from the inside out.
What Is Inflammaging—Really?
Inflammaging is a term scientists use to describe the chronic, low-grade inflammation that builds up in our bodies and tissues over time. Unlike the fiery redness of acute inflammation (like a cut or breakout), inflammaging is slow, quiet, and systemic.
Over time, this micro-inflammation interferes with how your cells:
Use energy
Repair damage
Make collagen and elastin
Turn over dead skin
Flush toxins and maintain clarity
You’re not “just getting older”—you’re out of cellular rhythm.
What’s Really Driving It?
1. Chronic Stress
Prolonged cortisol elevation reduces collagen production, impairs wound healing, and activates inflammatory cytokines. Over time, the skin stays in a low-repair, high-alert state【1】.
2. Metabolic Dysfunction
Think of metabolism not as “how fast you burn calories,” but how efficiently your cells convert nutrients into energy. When mitochondrial function drops, your skin has less fuel to regenerate【2】.
Early signs?
Dull, tired skin
Puffiness or uneven tone
Slow healing
Reactivity despite a “clean” routine
Why Your Skin Isn’t Bouncing Back
Inflammaging damages the fibroblasts—the architects of collagen and elastin—through oxidative stress, inflammatory messengers, and even cortisol itself. One study showed fibroblasts exposed to inflammatory signals reduced collagen synthesis by over 50%【3】.
It also alters capillary health, impairing oxygen and nutrient delivery. Without a strong microcirculation network, skin looks faded—even when you’re eating and hydrating well.
And hormones? Absolutely involved. Declining estrogen, DHEA, and thyroid activity all slow cell renewal, while cortisol and insulin resistance accelerate breakdown.
Let’s Talk Regeneration
At Skin Reset Lab, we don’t “fight” aging. We rebuild the systems that keep skin vibrant. That starts with cellular energy.
Meet NAD+: The Molecule of Youth
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in every cell. It powers mitochondrial energy, DNA repair, and collagen production. But it declines by as much as 50% by age 40【4】.
Enter NMNH, a next-generation NAD+ precursor that helps the body naturally restore this repair molecule without the crash or flushing of other forms.
If your cells were a Tesla, NAD+ is the battery. No charge = no power = no performance.
Want Your Glow Back? Start Here:
1. Reignite Your Skin’s Energy Cycle
Daily NMNH (125–250 mg)
CoQ10 or PQQ to fuel mitochondria
Magnesium bisglycinate for cellular calm
These support real skin regeneration—not just surface hydration.
2. Upgrade Your Routine with Regenerative Ingredients
Skip the high-acid “anti-aging” fatigue. Go deeper.
Try:
Copper peptides – encourage angiogenesis and fibroblast activity
Bakuchiol – retinol alternative that boosts collagen with less irritation
EGCG (green tea extract) – protects telomeres, reduces inflammation
Tremella mushroom extract – a plant-based hydrator with antioxidant activity
Resveratrol – polyphenol that activates sirtuins, slows visible aging
3. Support Your Detox Organs
Chronic inflammation often starts with congestion in the gut, liver, and lymph.
Try this Spring Reset Infusion:
1 tsp dandelion root
1 tsp schisandra berries
1 tsp orange peel
Steep 10–15 minutes. Drink in the morning. Repeat for 7 days.
4. Regulate Stress to Regulate Skin
Try a 3-minute neurocalming reset before applying your evening skincare:
4-7-8 breath
Gua sha over temples and neck
Apply peptides or copper serum with warm hands
Close with a hand-to-heart hold (yes, it works)
Bonus: add tulsi or reishi tea and 8 hours of sleep. That’s regenerative skincare.
Want to Dig Deeper? Consider Functional Testing
If your skin isn’t responding and your labs are “normal,” here’s what we look at:
DUTCH Test – cortisol rhythm, estrogen, DHEA
GI-MAP – gut dysbiosis, inflammatory markers
Organic Acids Test or NutrEval – oxidative stress, mitochondrial function, nutrient status
These reveal what your skin is too polite to say out loud.
The Future of Beauty Is Regenerative
You don’t need to age backwards—you just need to age intelligently.
Give your skin what it actually wants: more power, less panic. More repair, less reaction. More rhythm, less rush.
You’re not falling apart. You’re ready to rebuild.
References
1. Slominski, A. et al. (2012). Cortisol and skin aging: neuroendocrine regulation of inflammation. Exp Dermatol.
2. Wallace, D. C. (2005). Mitochondria and aging. Science.
3. Quan, T. et al. (2010). Inflammation and dermal fibroblast function. J Invest Dermatol.
4. Gomes, A. et al. (2013). Declining NAD+ induces mitochondrial dysfunction and accelerates aging. Cell Metabolism.
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